Bioactive Suture

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Bioactive suture: a novel immunotherapy for head and neck cancer.

PURPOSE We have proposed to characterize the mechanism through which bioactive surgical sutures generate a T(H)1 immune response and to define the immune-stimulating half-life of the sutures. EXPERIMENTAL DESIGN Bioactive sutures of interferon gamma (IFNgamma), interleukin 2 (IL-2), anti-CD3/CD28, anti-CD3/CD28 + IL-2, or anti-CD3/CD28 + IFNgamma sutures were used to stimulate lymphocytes fro...

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Suture Anchors Fixation in MPFL Reconstruction using a Bioactive Synthetic Ligament

Medial patellofemoral ligament (MPFL) reconstruction has a key role in patellofemoral instability surgery. Many surgical techniques have been described so far using different types of grafts (autologous, heterologous, or synthetic) and fixation techniques. The hereby described technique for MPFL reconstruction relies on the use of a biosynthetic graft (LARS Arc Sur Tille, France). Fixation is o...

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ADJUSTABLE SUTURE IN STRABISMUS SURGERY

Adjustable suture in strabismus surgery is a way to get accurate alignment of the eyes after operation. This technique is used in cooperative patients, being either adults or children. We report the result of this technique in 120 patients, 70 with esotropia and 50 exotropia. The amount of deviation was between 20 and 60 prismdiopters. The patients were mostly adults and teenagers. and the...

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The effect of suture coated with mesenchymal stem cells and bioactive substrate on tendon repair strength in a rat model.

PURPOSE Exogenously administered mesenchymal stem cells and bioactive molecules are known to enhance tendon healing. Biomolecules have been successfully delivered using sutures that elute growth factors over time. We sought to evaluate the histologic and biomechanical effect of delivering both cells and bioactive substrates on a suture delivery vehicle in comparison with sutures coated with bio...

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ژورنال

عنوان ژورنال: Clinical Cancer Research

سال: 2004

ISSN: 1078-0432,1557-3265

DOI: 10.1158/1078-0432.ccr-04-0052